Peptide Database

AOD9604 (Advanced Obesity Drug 9604) is a modified fragment of human growth hormone (hGH fragment 176-191). It was developed at Monash University in Australia specifically to isolate the fat-reducing effects of GH without its growth-promoting or diabetogenic properties. It received GRAS (Generally Recognized as Safe) status from the FDA as a food ingredient.

BPC-157 (Body Protection Compound-157) is a pentadecapeptide consisting of 15 amino acids. It is a partial sequence of body protection compound (BPC) discovered in and isolated from human gastric juice. Research has primarily focused on its potential effects on tissue healing, gastrointestinal repair, and anti-inflammatory properties. Note: BPC-157 has not received FDA approval for any medical use. All information presented is based on published research and is for educational purposes only.

CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that extends its half-life. It was developed to increase GH and IGF-1 secretion while maintaining the natural pulsatile release pattern. Research focuses on its effects on body composition, recovery, and sleep quality.

DSIP (Delta-Sleep Inducing Peptide) is a nonapeptide discovered in 1974 from the blood of rabbits in an induced state of sleep. Research focuses on its potential to promote natural delta-wave (deep) sleep, modulate stress responses, and normalize sleep architecture. Its mechanisms remain incompletely understood.

Epitalon (Epithalon or Epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on epithalamin, a naturally occurring peptide produced by the pineal gland. Research by Professor Vladimir Khavinson focuses on its potential to activate telomerase, regulate melatonin production, and modulate biological aging processes.

GHK-Cu (copper peptide GHK-Cu, or glycyl-L-histidyl-L-lysine copper(II)) is a naturally occurring copper complex of the tripeptide GHK. It was first identified in human plasma and has been studied for its role in collagen synthesis, skin remodeling, wound healing, and potential gene expression modulation related to aging.

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified version of IGF-1 with 83 amino acids (compared to 70 in native IGF-1). The modifications include an arginine instead of glutamic acid at position 3 and a 13 amino acid extension at the N-terminus, resulting in reduced IGF binding protein affinity and extended half-life.

Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. It is considered one of the cleanest GH-releasing peptides due to its selective action on GH release without significantly affecting cortisol, prolactin, or other hormones. Research focuses on GH optimization, body composition, and recovery.

KPV is a tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte stimulating hormone (alpha-MSH). Research focuses on its potent anti-inflammatory properties, particularly in gastrointestinal inflammation and inflammatory bowel conditions.

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a mitochondrial-derived peptide consisting of 16 amino acids. It was discovered in 2015 and has been described as an exercise mimetic due to its effects on metabolic regulation, insulin sensitivity, and physical performance.

Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH). It was originally developed at the University of Arizona for skin cancer prevention through tanning without UV exposure. Research has also explored its effects on sexual function and appetite suppression. It is NOT FDA-approved for any use.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells. It is essential for cellular energy production, DNA repair, gene expression regulation, and calcium signaling. NAD+ levels naturally decline with age, and research focuses on restoring levels through supplementation with NAD+ precursors (NMN, NR) or direct IV administration.

Oxytocin is a naturally occurring nonapeptide hormone produced in the hypothalamus. FDA-approved (Pitocin®) for labor induction and postpartum hemorrhage management. Research also explores its roles in social bonding, trust, anxiety reduction, and various neuropsychiatric conditions.

PT-141 (Bremelanotide, brand name Vyleesi®) is a synthetic melanocortin peptide and MC4 receptor agonist. It is FDA-approved for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. Unlike PDE5 inhibitors, it works through central nervous system pathways rather than vascular mechanisms.

Retatrutide (LY3437943) is a triple agonist peptide targeting GIP, GLP-1, and glucagon receptors. Developed by Eli Lilly, it represents the next generation of incretin-based therapies. Phase 2 clinical trials have shown unprecedented weight loss results, and Phase 3 trials are ongoing.

SS-31 (also known as Elamipretide or Bendavia) is a mitochondria-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2). It selectively concentrates in the inner mitochondrial membrane and has been studied for mitochondrial dysfunction, aging, and various age-related conditions. It is currently in clinical trials for multiple indications.

Selank is a synthetic analog of the naturally occurring immunomodulatory peptide tuftsin, developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It has been studied for anxiolytic (anti-anxiety), nootropic (cognitive-enhancing), and immunomodulatory properties. It is approved in Russia as a nasal spray for anxiety and neurasthenia.

Semaglutide is a GLP-1 receptor agonist FDA-approved under brand names Ozempic® (T2D), Wegovy® (weight management), and Rybelsus® (oral T2D). It represents a major advance in metabolic medicine with demonstrated efficacy for glycemic control, weight management, and cardiovascular risk reduction.

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone), specifically the fragment ACTH(4-7) with the addition of Pro-Gly-Pro. Developed at the Institute of Molecular Genetics, Russian Academy of Sciences, it has been studied for neuroprotective, nootropic, and neurotrophic properties. It is approved in Russia and Ukraine for stroke, cognitive disorders, and optic nerve diseases.

TB-500 is a synthetic version of a region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide present in virtually all human cells. Thymosin Beta-4 plays a crucial role in tissue repair, cell migration, and blood vessel formation. TB-500 research focuses on wound healing, anti-inflammatory properties, and tissue regeneration.

Tesamorelin (brand name Egrifta®) is a synthetic analog of growth hormone-releasing hormone (GHRH). It is FDA-approved for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. It stimulates the pituitary gland to produce growth hormone.

Tirzepatide (brand names Mounjaro® for T2D, Zepbound® for weight management) is a dual GIP and GLP-1 receptor agonist developed by Eli Lilly. It is FDA-approved for type 2 diabetes management and chronic weight management in adults with obesity or overweight with at least one weight-related condition.